Peptiv8 Retatrutide 40mg Multi-Dose Research Pen — Instructions for Research Use

1 Important Research‑Use Notice

This product is not a medicine, medical device, food, cosmetic, or dietary supplement.

For controlled laboratory research use only.
Not intended to diagnose, treat, cure, prevent, or mitigate any disease or condition.
Do not use for self‑administration or administration to another person.
Use only by trained personnel in an authorised research setting.

This sheet supports controlled handling and recordkeeping. It does not replace the batch Certificate of Analysis, Safety Data Sheet, validated study protocol, or applicable laws and regulations.

2 Before Handling

Confirm the label reads Retatrutide 40mg Multi‑Dose Research Pen.

Match the batch number to the Certificate of Analysis.

Inspect the pen for leakage, cracks, contamination, or missing cap.

Confirm the visible solution matches the batch documentation.

Verify storage conditions and expiry/retest status.

Prepare PPE, collection vessels, waste containers, and the laboratory record.

Do not continue if the pen is damaged, leaking, unlabeled, contaminated, or outside the stated storage conditions. Quarantine and contact Peptiv8 Support.

3 Pen Overview

The Peptiv8 multi‑dose research pen uses an adjustable clicker mechanism to dispense measured research volumes from a prefilled cartridge into an approved laboratory receiving vessel, assay substrate, or validated collection target.

Guide to parts

Parts of the Peptiv8 multi-dose research pen

0

Pen Cap

Cap Clip

Cartridge

Cartridge
Holder

Plunger

Pen Body

Label

Dose Indicator

Dose
Window

Dose Knob
/ Clicker

Typical components

Pen cap
Cartridge holder / inspection window
Product label and batch details
Dose selector or dose mechanism
Dose indicator
Dispense button
Pen tip / accessory connection area

Handling limits

Do not modify, disassemble, refill, repair, or recalibrate the pen.
Use only compatible sterile laboratory accessories if required.
Keep capped until controlled laboratory dispensing.
Protect from contamination, direct light, excessive heat, and unauthorised access.

4 Adjustable Clicker Calibration

The pen contains a nominal total of 40mg retatrutide. Output is adjusted using the clicker mechanism, with click count used to reconcile intended research volume and nominal retatrutide content.

A 60 IU / 60 click setting is calibrated as 0.6mL and contains 10mg retatrutide nominal content.

Reference setting	Nominal content	Record requirement
60 clicks / 60 IU	10mg retatrutide / 0.6mL	Date/time, batch, operator, click count, receiving vessel/test ID
Adjustable partial setting	See click / volume table below	Date/time, batch, operator, click count, receiving vessel/test ID

5 Click / Volume Reference

Use this reference to reconcile the pen click count, volume, and nominal retatrutide content in the laboratory record. These values are for controlled research measurement only and are not administration guidance.

Calibration basis: 60 clicks = 60 IU = 0.6mL = 10mg retatrutide. Lower click counts represent proportional measured research volumes.

Clicks / IU	Volume	Nominal retatrutide content
1 click / 1 IU	0.01mL	0.167mg / 166.7mcg
6 clicks / 6 IU	0.06mL	1mg
12 clicks / 12 IU	0.12mL	2mg
18 clicks / 18 IU	0.18mL	3mg
24 clicks / 24 IU	0.24mL	4mg
30 clicks / 30 IU	0.30mL	5mg
36 clicks / 36 IU	0.36mL	6mg
42 clicks / 42 IU	0.42mL	7mg
48 clicks / 48 IU	0.48mL	8mg
54 clicks / 54 IU	0.54mL	9mg
60 clicks / 60 IU	0.60mL	10mg

6 Controlled Laboratory Dispensing

Confirm the required click count and receiving vessel/test system ID.
Put on required PPE and prepare the approved collection vessel, substrate, or target.
Remove the pen cap and attach any compatible sterile accessory required by the pen configuration.
Set or confirm the required click count on the dose mechanism.
Direct the dispensing end into the approved receiving vessel, substrate, or validated collection target.
Activate the dispense mechanism fully and maintain position until the validated workflow indicates completion.
Confirm the dose mechanism indicates completion for the selected click count.
Dispose of any single‑use accessory according to local laboratory procedure.
Recap the pen, return it to required storage, and complete the laboratory record.

Do not estimate, recover, or re‑dispense a suspected partial aliquot unless the validated research protocol specifically describes that deviation process.

7 Flow Check and Deviations

Flow check

If a flow check is required, perform it only into an approved waste vessel or collection material. Confirm liquid appears from the dispensing pathway before study use. If flow is not confirmed, quarantine the pen.

Deviation handling

Record leakage, blocked flow, dropped pen, suspected contamination, or incomplete dispense in the study record. Stop use until the protocol or Peptiv8 Support provides direction.

8 Storage and Disposal

Storage

Follow batch-specific storage conditions supplied with the COA/SDS.
Keep capped when not in use.
Protect from direct light, excessive heat, and uncontrolled conditions.
Store in controlled-access research storage only.

Disposal

Dispose of sharps in an approved sharps container.
Dispose of contaminated material under institutional waste rules.
Do not place used accessories or contaminated materials in general waste.
Do not recycle, refill, or reuse the pen.

9 Troubleshooting

Observation	Action
No liquid appears during flow check	Confirm accessory attachment and remaining aliquots. Repeat only if permitted by protocol. If unresolved, quarantine.
Pen leaks	Stop use, place in secondary containment, record the event, and contact support.
Dose mechanism will not move	Do not force. Confirm remaining aliquots. Quarantine if resistance persists.
Incomplete dispense suspected	Do not uncontrolled re‑dispense. Record the observation and follow protocol deviation process.
Pen dropped or contaminated	Stop use unless recovery is explicitly permitted by protocol. Quarantine and record incident.

10 Support and Document Control

For product or batch questions, contact Peptiv8 Support with order number, batch number, relevant label photo, storage history if relevant, and a clear description of the issue.

Telegram Support: @Peptiv8Support

Document title: Peptiv8 Retatrutide 40mg Multi‑Dose Research Pen — Instructions for Research Use. Version: v1.0. Effective date: May 2026. Digital document only. This document is an original Peptiv8 research handling sheet and is not a patient medicine leaflet.